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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1831 | StemRegenin 1 | SR1 | AhR , Aryl Hydrocarbon Receptor |
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor. | |||
T23384 | SR 11302 | DNA/RNA Synthesis | |
SR 11302 is an inhibitor of activator protein-1 (AP-1). | |||
T12075 | ML-180 | SR1848 | Others |
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) . | |||
T1615 | Irbesartan | SR-47436,BMS-186295 | Apoptosis , RAAS |
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist. | |||
T14667 | BLT-1 | Others , HCV Protease | |
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor. | |||
T26221 | MCT1-IN-2 | SR13800,SR-13800,SR 13800 | |
SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable. | |||
T28041 | Mimopezil | ZT-1 LA,Debio-9902-SR,Debio-9902,ZT-1 | |
Mimopezil is an acetylcholinesterase (AChE) inhibitor. | |||
T16074 | Mifobate | SR-202 | PPAR |
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1]. | |||
T1519 | Rimonabant hydrochloride | SR 151716A,SR 141716A | Cannabinoid Receptor , Antibacterial |
Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity. | |||
T28847 | SR-17398 | ||
SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM). | |||
T81107 | SR-29065 | ||
SR-29065 is a selective agonist of REV-ERBα, utilized in the research of autoimmune disorders [1]. | |||
T80770 | Wt hMLN TFA | ||
WT hMLN (TFA) is a microprotein that functions as an inhibitor of the SR Ca2+ pump (SERCA), playing a crucial role in the regulation of calcium homeostasis in skeletal muscle [1]. | |||
T69671 | SR1903 TFA | ||
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated rec... | |||
T35638 | SR 1903 | ||
SR 1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR).1 It is an inverse agonist of RORγ (IC50 = ~100 nM in a cell-based reporter assay) and an agonist of LXR. It al... | |||
T74489 | SIAIS117 | ||
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell li... | |||
T81108 | SR-1114 | PROTACs | |
SR-1114, a first-in-class PROTAC ENL degrader, induces rapid CRBN-dependent ENL degradation with DC50 values of 150 nM in MV4;11 cells, 311 nM in MOLM-13 cells, and 1.65 μM in OCI/AML-2 cells [1]. | |||
T71009 | Dolutegravir SR Isomer | ||
Dolutegravir SR Isomer is an isomeric derivative of Dolutegravir -- a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripher... | |||
T76872 | Neihulizumab | ||
Neihulizumab (ALTB-168), an immune checkpoint agonistic antibody, targets and binds to human CD162 (PSGL-1), resulting in the downregulation of activated T-cells. It is utilized in research aimed at treating steroid-refr... | |||
T37449 | SR 12460 | ||
SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits T... | |||
T83422 | 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine | ||
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine, a glycerophosphorylcholine derivative, comprises glycerol phosphate, choline, and palmitic acid and accumulates at oxidative stress sites in vivo. It potentially acts a... |