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Search Results for " sr 1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T1831 StemRegenin 1 SR1 AhR , Aryl Hydrocarbon Receptor
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.
T23384 SR 11302 DNA/RNA Synthesis
SR 11302 is an inhibitor of activator protein-1 (AP-1).
T12075 ML-180 SR1848 Others
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .
T1615 Irbesartan SR-47436,BMS-186295 Apoptosis , RAAS
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T14667 BLT-1 Others , HCV Protease
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.
T26221 MCT1-IN-2 SR13800,SR-13800,SR 13800
SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.
T28041 Mimopezil ZT-1 LA,Debio-9902-SR,Debio-9902,ZT-1
Mimopezil is an acetylcholinesterase (AChE) inhibitor.
T16074 Mifobate SR-202 PPAR
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].
T1519 Rimonabant hydrochloride SR 151716A,SR 141716A Cannabinoid Receptor , Antibacterial
Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity.
T28847 SR-17398
SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).
T81107 SR-29065
SR-29065 is a selective agonist of REV-ERBα, utilized in the research of autoimmune disorders [1].
T80770 Wt hMLN TFA
WT hMLN (TFA) is a microprotein that functions as an inhibitor of the SR Ca2+ pump (SERCA), playing a crucial role in the regulation of calcium homeostasis in skeletal muscle [1].
T69671 SR1903 TFA
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated rec...
T35638 SR 1903
SR 1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR).1 It is an inverse agonist of RORγ (IC50 = ~100 nM in a cell-based reporter assay) and an agonist of LXR. It al...
T74489 SIAIS117
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell li...
T81108 SR-1114 PROTACs
SR-1114, a first-in-class PROTAC ENL degrader, induces rapid CRBN-dependent ENL degradation with DC50 values of 150 nM in MV4;11 cells, 311 nM in MOLM-13 cells, and 1.65 μM in OCI/AML-2 cells [1].
T71009 Dolutegravir SR Isomer
Dolutegravir SR Isomer is an isomeric derivative of Dolutegravir -- a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripher...
T76872 Neihulizumab
Neihulizumab (ALTB-168), an immune checkpoint agonistic antibody, targets and binds to human CD162 (PSGL-1), resulting in the downregulation of activated T-cells. It is utilized in research aimed at treating steroid-refr...
T37449 SR 12460
SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits T...
T83422 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine, a glycerophosphorylcholine derivative, comprises glycerol phosphate, choline, and palmitic acid and accumulates at oxidative stress sites in vivo. It potentially acts a...
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